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Cephalosporin C zinc salt

CAS No. 59143-60-1

Cephalosporin C zinc salt( —— )

Catalog No. M20689 CAS No. 59143-60-1

Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 μM) and this inhibition was largely attributable to the presence of zinc.?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Cephalosporin C zinc salt
  • Note
    Research use only, not for human use.
  • Brief Description
    Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 μM) and this inhibition was largely attributable to the presence of zinc.?
  • Description
    Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 μM) and this inhibition was largely attributable to the presence of zinc.?
  • In Vitro
    Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 ± 0.1 μM, 200-fold more potent than Na+ salt form of Cephalosporin C (ICC50CC-Na = 213 ± 30 μM).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SAMHD1?
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    59143-60-1
  • Formula Weight
    478.78
  • Molecular Formula
    C16H19N3O8SZn
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:6 mg/mL (12.53 mM)
  • SMILES
    [Zn++].[H][C@@]12SCC(CC(C)=O)=C(N1C(=O)[C@H]2NC(=O)CCC[C@@H](N)C([O-])=O)C([O-])=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Seamon K J Stivers J T . A high-throughput enzyme-coupled assay for SAMHD1 dNTPase[J]. Journal of Biomolecular Screening 2015 20(6).
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